Enrichment analysis of genes dysregulated in LMNA LMNA H222P heterozygous knock in mutation
Canned Analysis
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General Information
AccessionDCA00024334
TitleEnrichment analysis of genes dysregulated in LMNA LMNA H222P heterozygous knock in mutation
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between LMNA LMNA H222P heterozygous knock in mutation cells and control cells in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3095372
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcms
CREEDS IDgene:1312
Cell Typeheart
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismmouse
Perturbation TypeLMNA H222P heterozygous knock in mutation
Characteristic Direction parameters
Control SamplesGSM147451, GSM147452, GSM147459, GSM147460, GSM147461, GSM147462, GSM147463, GSM147465
Perturbed SamplesGSM147506, GSM147507, GSM147509, GSM147510, GSM147511, GSM147512, GSM147513
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6397
Gene Expression Omnibus
Comparison between gene expression in heart from Lmna H222P heterozygous and control mice
5
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