Enrichment analysis of genes dysregulated in AHR low-affinity mutant
Canned Analysis
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General Information
AccessionDCA00024469
TitleEnrichment analysis of genes dysregulated in AHR low-affinity mutant
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between AHR low-affinity mutant cells and control cells in the bone marrow derived mast cells (BMMCs) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3090404
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1467
Cell Typebone marrow derived mast cells (BMMCs)
Gene Symbol (human)AHR
Gene Symbol (mouse)Ahr
Organismmouse
Perturbation Typelow-affinity mutant
Characteristic Direction parameters
Control SamplesGSM1089253, GSM1089254, GSM1089255
Perturbed SamplesGSM1089247, GSM1089248, GSM1089249
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44715
Gene Expression Omnibus
Mast cell expression data from murine aryl hydrocarbon receptor (AhR) null, AhR_d and normal control mice
14
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