Enrichment analysis of genes dysregulated in PIK3CA mutant
Canned Analysis
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General Information
AccessionDCA00024502
TitleEnrichment analysis of genes dysregulated in PIK3CA mutant
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between PIK3CA mutant cells and control cells in the ER+ breast tumor cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3090808
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1873
Cell TypeER+ breast tumor
Gene Symbol (human)PIK3CA
Gene Symbol (mouse)Pik3ca
Organismhuman
Perturbation Typemutant
Characteristic Direction parameters
Control SamplesGSM547768, GSM547769, GSM547770, GSM547771, GSM547776, GSM547779, GSM547780, GSM547781, GSM547782, GSM547784, GSM547785, GSM547786, GSM547787, GSM547788, GSM547789, GSM547790, GSM547791, GSM547793, GSM547795, GSM547796, GSM547797, GSM547798, GSM547801, GS
Perturbed SamplesGSM547772, GSM547773, GSM547774, GSM547775, GSM547777, GSM547778, GSM547783, GSM547792, GSM547794, GSM547799, GSM547800, GSM547806, GSM547807, GSM547809
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22035
Gene Expression Omnibus
Postmenopausal estrogen receptor -positive breast tumor with PIK3CA mutation
14
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