Enrichment analysis of genes dysregulated in KMT2A MLL chromosomal translocation (tMLL) compared to partial tandem
Canned Analysis
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General Information
AccessionDCA00024505
TitleEnrichment analysis of genes dysregulated in KMT2A MLL chromosomal translocation (tMLL) compared to partial tandem
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between KMT2A MLL chromosomal translocation (tMLL) compared to partial tandem cells and control cells in the bone marrow mononuclear cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3094023
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:1506
Cell Typebone marrow mononuclear cells
Gene Symbol (human)KMT2A
Gene Symbol (mouse)Kmt2a
Organismhuman
Perturbation TypeMLL chromosomal translocation (tMLL) compared to partial tandem
Characteristic Direction parameters
Control SamplesGSM304968, GSM307951, GSM307952, GSM307953, GSM307957, GSM307958, GSM307959, GSM307960, GSM307961, GSM307966
Perturbed SamplesGSM366160, GSM366161, GSM366162, GSM366163, GSM366164, GSM366165, GSM366166, GSM366167, GSM366168, GSM366169, GSM366170, GSM366171, GSM366172, GSM366173, GSM366174
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15013
Gene Expression Omnibus
Mixed lineage leukemia gene rearrangements in acute myeloid leukemia: bone marrow mononuclear cells
7
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