Enrichment analysis of genes dysregulated in LMNA KO
Canned Analysis
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General Information
AccessionDCA00024512
TitleEnrichment analysis of genes dysregulated in LMNA KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between LMNA KO cells and control cells in the whole heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3093471
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1518
Cell Typewhole heart
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM147451, GSM147452, GSM147459, GSM147460, GSM147461, GSM147462, GSM147463, GSM147465
Perturbed SamplesGSM147514, GSM147515, GSM147516, GSM147517, GSM147518, GSM147519
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8000
Gene Expression Omnibus
Lmna H222P homozygous and heterozygous mutant models of Emery-Dreifuss muscular dystrophy: hearts
19
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