Enrichment analysis of genes dysregulated in STAT1 Stat1 delta beta (db), deficient for STAT1 dimer without C-termi
Canned Analysis
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General Information
AccessionDCA00024515
TitleEnrichment analysis of genes dysregulated in STAT1 Stat1 delta beta (db), deficient for STAT1 dimer without C-termi
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between STAT1 Stat1 delta beta (db), deficient for STAT1 dimer without C-termi cells and control cells in the bone marrow macrophages (BMMs) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092910
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1521
Cell Typebone marrow macrophages (BMMs)
Gene Symbol (human)STAT1
Gene Symbol (mouse)Stat1
Organismmouse
Perturbation TypeStat1 delta beta (db), deficient for STAT1 dimer without C-termi
Characteristic Direction parameters
Control SamplesGSM1190948, GSM1190952, GSM1190956
Perturbed SamplesGSM1190946, GSM1190950, GSM1190954
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE48970
Gene Expression Omnibus
Contribution of the STAT1alpha and STAT1beta isoforms to IFN-gamma mediated innate immunity
21
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