Enrichment analysis of genes dysregulated in BATF KO
Canned Analysis
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General Information
AccessionDCA00024518
TitleEnrichment analysis of genes dysregulated in BATF KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between BATF KO cells and control cells in the 3 day in vitro effector CD8+ T cells--Naïve CD8+ T cells (P14 TCR transgenic C57Bl/6) were stimulated with plate-bound anti-CD3 (4 mg/ml, clone 2C11, BD Pharmingen) and anti-CD28 (4 mg/ml, clone 37.51, BD Pharmingen) in the presence of recombinant human IL-2 (100 U/ml, R&D Systems) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092904
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1523
Cell Type3 day in vitro effector CD8+ T cells--Naïve CD8+ T cells (P14 TCR transgenic C57Bl/6) were stimulated with plate-bound anti-CD3 (4 mg/ml, clone 2C11, BD Pharmingen) and anti-CD28 (4 mg/ml, clone 37.51, BD Pharmingen) in the presence of recomb
Gene Symbol (human)BATF
Gene Symbol (mouse)Batf
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM1310344, GSM1310345, GSM1310346, GSM1310347
Perturbed SamplesGSM1310348, GSM1310349, GSM1310350, GSM1310351
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54215
Gene Expression Omnibus
Comparison of gene expression profiles of nave and in vitro effector CD8+ T cells from wild-type and BATF-/- mice
14
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