Enrichment analysis of genes dysregulated in IRAK2 knockout
Canned Analysis
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General Information
AccessionDCA00024824
TitleEnrichment analysis of genes dysregulated in IRAK2 knockout
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between IRAK2 knockout cells and control cells in the macrophages stimulated with MALP-2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3094420
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1884
Cell Typemacrophages stimulated with MALP-2
Gene Symbol (human)IRAK2
Gene Symbol (mouse)Irak2
Organismmouse
Perturbation Typeknockout
Characteristic Direction parameters
Control SamplesGSM271850, GSM271851, GSM271852, GSM271853
Perturbed SamplesGSM271854, GSM271855, GSM271856, GSM271857
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10765
Gene Expression Omnibus
Expression data from MALP-2-stimulated macrophages from wild-type, IRAK-2-/- and IRAK-1-/IRAK-2-/- mice
7
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