Enrichment analysis of genes dysregulated in IGF1R druginhibition
Canned Analysis
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General Information
AccessionDCA00024825
TitleEnrichment analysis of genes dysregulated in IGF1R druginhibition
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between IGF1R druginhibition cells and control cells in the 3T3 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3094426
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1886
Cell Type3T3
Gene Symbol (human)IGF1R
Gene Symbol (mouse)Igf1r
Organismmouse
Perturbation Typedruginhibition
Characteristic Direction parameters
Control SamplesGSM352188, GSM352189, GSM352190
Perturbed SamplesGSM352191, GSM352192, GSM352193
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE14024
Gene Expression Omnibus
Reversal of oncogene transformation and suppression of tumor growth by the novel IGF1R kinase inhibitor A-928605.
14
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