Enrichment analysis of genes dysregulated in JAK2 activemutant
Canned Analysis
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General Information
AccessionDCA00024845
TitleEnrichment analysis of genes dysregulated in JAK2 activemutant
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between JAK2 activemutant cells and control cells in the LSK cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3090734
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1901
Cell TypeLSK cells
Gene Symbol (human)JAK2
Gene Symbol (mouse)Jak2
Organismmouse
Perturbation Typeactivemutant
Characteristic Direction parameters
Control SamplesGSM543489, GSM543490, GSM543491, GSM543492
Perturbed SamplesGSM543493, GSM543494, GSM543495, GSM543496
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE21842
Gene Expression Omnibus
Physiological Jak2V617F expression causes a lethal myeloproliferative neoplasm with differential effects on hematopoietic stem and progenitor cells
7
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