Enrichment analysis of genes dysregulated in SYK druginhibition
Canned Analysis
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General Information
AccessionDCA00024866
TitleEnrichment analysis of genes dysregulated in SYK druginhibition
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between SYK druginhibition cells and control cells in the DHL6 or DHL4 diffuse large b-cell lymphoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3096154
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1931
Cell TypeDHL6 or DHL4 diffuse large b-cell lymphoma cell line
Gene Symbol (human)SYK
Gene Symbol (mouse)Syk
Organismhuman
Perturbation Typedruginhibition
Characteristic Direction parameters
Control SamplesGSM843447, GSM843448, GSM843449, GSM843450, GSM843451
Perturbed SamplesGSM843458, GSM843459, GSM843460, GSM843461, GSM843462, GSM843463
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE34176
Gene Expression Omnibus
Spleen tyrosine kinase inhibitor effect on diffuse large B-cell lymphoma cell lines: time course
28
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