Enrichment analysis of genes dysregulated in MAP2K1 druginhibition
Canned Analysis
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General Information
AccessionDCA00024876
TitleEnrichment analysis of genes dysregulated in MAP2K1 druginhibition
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between MAP2K1 druginhibition cells and control cells in the mouse melanoma model cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3095678
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1944
Cell Typemouse melanoma model
Gene Symbol (human)MAP2K1
Gene Symbol (mouse)Map2k1
Organismmouse
Perturbation Typedruginhibition
Characteristic Direction parameters
Control SamplesGSM982953, GSM982954, GSM982955, GSM982956, GSM982957, GSM982958
Perturbed SamplesGSM982965, GSM982966, GSM982967, GSM982968, GSM982969, GSM982970
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39984
Gene Expression Omnibus
Comparison of the genetic extinction of NRAS to pharmacological MEK inhibition in an inducible mouse model of melanoma
7
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