Enrichment analysis of genes dysregulated in HIF1A KD
Canned Analysis
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General Information
AccessionDCA00025061
TitleEnrichment analysis of genes dysregulated in HIF1A KD
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between HIF1A KD cells and control cells in the Heptaocellular carcinoma cell line HepG2 cells were infected with S. aureus 8325-4 (MOI: 20) for four hours (5 % CO2, 96 % humidity and 37 °C) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3091654
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2235
Cell TypeHeptaocellular carcinoma cell line HepG2 cells were infected with S. aureus 8325-4 (MOI: 20) for four hours (5 % CO2, 96 % humidity and 37 °C)
Gene Symbol (human)HIF1A
Gene Symbol (mouse)Hif1a
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Control SamplesGSM1094268, GSM1094269, GSM1094270
Perturbed SamplesGSM1094262, GSM1094263, GSM1094264
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44943
Gene Expression Omnibus
HIF-1 dependent gene expression upon S. aureus infection
14
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