Enrichment analysis of genes dysregulated in LMNA HGPS single-point mutation
Canned Analysis
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General Information
AccessionDCA00025081
TitleEnrichment analysis of genes dysregulated in LMNA HGPS single-point mutation
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between LMNA HGPS single-point mutation cells and control cells in the fibroblasts (bj-fib_2 and HGPS-fib_2) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3094925
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2257
Cell Typefibroblasts (bj-fib_2 and HGPS-fib_2)
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismhuman
Perturbation TypeHGPS single-point mutation
Characteristic Direction parameters
Control SamplesGSM603015, GSM603043
Perturbed SamplesGSM603044, GSM603045
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24487
Gene Expression Omnibus
Induced pluripotent stem cell-based accelerated aging model
14
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