Enrichment analysis of genes dysregulated in PRMT5 KO
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00025203
TitleEnrichment analysis of genes dysregulated in PRMT5 KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between PRMT5 KO cells and control cells in the Neural stem/ progenitor cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092236
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorRuta
CREEDS IDgene:2403
Cell TypeNeural stem/ progenitor cells
Gene Symbol (human)PRMT5
Gene Symbol (mouse)Prmt5
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM1100469, GSM1100470, GSM1100471, GSM1100472
Perturbed SamplesGSM1100473, GSM1100474, GSM1100475, GSM1100476
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE45269
Gene Expression Omnibus
Regulation of constitutive and alternative splicing by PRMT5 reveals a role for Mdm4 pre-mRNA in sensing defects in the spliceosomal machinery (BeadCh...
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.