Enrichment analysis of genes dysregulated in CYP27B1 KO
Canned Analysis
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General Information
AccessionDCA00025204
TitleEnrichment analysis of genes dysregulated in CYP27B1 KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between CYP27B1 KO cells and control cells in the genotype/variation: Cyp27b1 flox/flox;Cre+ OR Cre- tissue: breast tumor genetic background: FVB cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092239
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2404
Cell Typegenotype/variation: Cyp27b1 flox/flox;Cre+ OR Cre- tissue: breast tumor genetic background: FVB
Gene Symbol (human)CYP27B1
Gene Symbol (mouse)Cyp27b1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM992462, GSM992463, GSM992464
Perturbed SamplesGSM992465, GSM992466, GSM992467
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40375
Gene Expression Omnibus
Lack of local vitamin D synthesis accelerates breast cancer development after Cyp27B1 gene ablation in mammary epithelium
7
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