Enrichment analysis of genes dysregulated in CFTR D508 mutation
Canned Analysis
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General Information
AccessionDCA00025229
TitleEnrichment analysis of genes dysregulated in CFTR D508 mutation
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between CFTR D508 mutation cells and control cells in the rectal mucosal epithelia cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3091474
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2425
Cell Typerectal mucosal epithelia
Gene Symbol (human)CFTR
Gene Symbol (mouse)Cftr
Organismhuman
Perturbation TypeD508 mutation
Characteristic Direction parameters
Control SamplesGSM389668, GSM389669, GSM389670, GSM389671, GSM389672, GSM389673, GSM389674, GSM389675, GSM389676, GSM389677, GSM389678, GSM389679, GSM389680
Perturbed SamplesGSM389652, GSM389653, GSM389654, GSM389655, GSM389656, GSM389657, GSM389658, GSM389659, GSM389660, GSM389661, GSM389662, GSM389663, GSM389664, GSM389665, GSM389666, GSM389667
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE15568
Gene Expression Omnibus
Cystic fibrosis: rectal epithelia
12
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