Enrichment analysis of genes dysregulated in THRB d337T mutation - dominant negative
Canned Analysis
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General Information
AccessionDCA00025238
TitleEnrichment analysis of genes dysregulated in THRB d337T mutation - dominant negative
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between THRB d337T mutation - dominant negative cells and control cells in the heart cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3090895
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2435
Cell Typeheart
Gene Symbol (human)THRB
Gene Symbol (mouse)Thrb
Organismmouse
Perturbation Typed337T mutation - dominant negative
Characteristic Direction parameters
Control SamplesGSM67362, GSM67363, GSM67364, GSM67365, GSM67366, GSM67367, GSM67368
Perturbed SamplesGSM67369, GSM67370, GSM67371, GSM67372, GSM67373, GSM67374, GSM67375
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3067
Gene Expression Omnibus
Dominant negative thyroid hormone receptor expression and PPARalpha activation effect on the heart
14
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