Enrichment analysis of genes dysregulated in SOCS3 KO
Canned Analysis
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General Information
AccessionDCA00025255
TitleEnrichment analysis of genes dysregulated in SOCS3 KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between SOCS3 KO cells and control cells in the Macrophages stimulated for 400 minutes with IL-6 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3093033
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAliDot
CREEDS IDgene:2456
Cell TypeMacrophages stimulated for 400 minutes with IL-6
Gene Symbol (human)SOCS3
Gene Symbol (mouse)Socs3
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM6074, GSM6080, GSM6085
Perturbed SamplesGSM6077, GSM6083, GSM6088
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE411
Gene Expression Omnibus
Macrophage response to IL-6, and SOCS3 effect
14
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