Enrichment analysis of genes dysregulated in MECP2 heterozygous de novo RTT mutations
Canned Analysis
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General Information
AccessionDCA00025271
TitleEnrichment analysis of genes dysregulated in MECP2 heterozygous de novo RTT mutations
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between MECP2 heterozygous de novo RTT mutations cells and control cells in the Superior Frontal Gyrus cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092753
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2473
Cell TypeSuperior Frontal Gyrus
Gene Symbol (human)MECP2
Gene Symbol (mouse)Mecp2
Organismhuman
Perturbation Typeheterozygous de novo RTT mutations
Characteristic Direction parameters
Control SamplesGSM160306, GSM160308, GSM160310
Perturbed SamplesGSM160307, GSM160309, GSM160311
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6955
Gene Expression Omnibus
Rett syndrome: brain frontal cortex
12
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