Enrichment analysis of genes dysregulated in FH Heterozygous germline mutations
Canned Analysis
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General Information
AccessionDCA00025292
TitleEnrichment analysis of genes dysregulated in FH Heterozygous germline mutations
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between FH Heterozygous germline mutations cells and control cells in the uterine fibroid and Myometrium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3096101
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:2489
Cell Typeuterine fibroid and Myometrium
Gene Symbol (human)FH
Gene Symbol (mouse)Fh1
Organismhuman
Perturbation TypeHeterozygous germline mutations
Characteristic Direction parameters
Control SamplesGSM52661, GSM52662, GSM52663, GSM52664, GSM52665, GSM52666, GSM52667, GSM52668, GSM52669, GSM52670, GSM52671
Perturbed SamplesGSM38689, GSM38690, GSM38691, GSM38692, GSM38693, GSM38694, GSM38695
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2724
Gene Expression Omnibus
Uterine fibroids with mutated fumarate hydratase (I)
12
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