Enrichment analysis of genes dysregulated in AIRE KO
Canned Analysis
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General Information
AccessionDCA00025456
TitleEnrichment analysis of genes dysregulated in AIRE KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between AIRE KO cells and control cells in the Medullary thymic epithelial cells (with low CD80 expression) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3096542
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:272
Cell TypeMedullary thymic epithelial cells (with low CD80 expression)
Gene Symbol (human)AIRE
Gene Symbol (mouse)Aire
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM49737, GSM49738
Perturbed SamplesGSM49733, GSM49734
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2585
Gene Expression Omnibus
Transcription factor Aire deficiency effect on medullary thymic epithelial cells
14
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