Enrichment analysis of genes dysregulated in SOX10 KO
Canned Analysis
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General Information
AccessionDCA00025562
TitleEnrichment analysis of genes dysregulated in SOX10 KO
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between SOX10 KO cells and control cells in the Schwannoma cell line. NB: This is actually a rat dataset, but I "chose" mouse because mouse is more similar to rats than man and there was no drop down option for Rattus norvegicus. cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3095020
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortpaunesku
CREEDS IDgene:284
Cell TypeSchwannoma cell line. NB: This is actually a rat dataset, but I "chose" mouse because mouse is more similar to rats than man and there was no drop down option for Rattus norvegicus.
Gene Symbol (human)SOX10
Gene Symbol (mouse)Sox10
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Control SamplesGSM303510, GSM303512
Perturbed SamplesGSM303507, GSM303511
Tools used in the analysis
Dataset Accession
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Datasets used in the analysis
Keyword
Tool Name
GSE12007
Gene Expression Omnibus
Sox10 depletion effect on Schwannoma cell line
7
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