Enrichment analysis of genes dysregulated in HTT knock-in
Canned Analysis
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General Information
AccessionDCA00025664
TitleEnrichment analysis of genes dysregulated in HTT knock-in
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between HTT knock-in cells and control cells in the tissue-specific / cerebellum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3092828
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormtahay
CREEDS IDgene:817
Cell Typetissue-specific / cerebellum
Gene Symbol (human)HTT
Gene Symbol (mouse)Htt
Organismmouse
Perturbation Typeknock-in
Characteristic Direction parameters
Control SamplesGSM229456, GSM229457, GSM229458
Perturbed SamplesGSM229459, GSM229460, GSM229461
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19780
Gene Expression Omnibus
HdhQ111 knock-in model of Huntington's disease: striatum and cerebellum
24
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