Enrichment analysis of genes dysregulated in BTK Missense mutation R28C
Canned Analysis
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General Information
AccessionDCA00025807
TitleEnrichment analysis of genes dysregulated in BTK Missense mutation R28C
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between BTK Missense mutation R28C cells and control cells in the splenic B cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3093396
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorXavier
CREEDS IDgene:976
Cell Typesplenic B cells
Gene Symbol (human)BTK
Gene Symbol (mouse)Btk
Organismmouse
Perturbation TypeMissense mutation R28C
Characteristic Direction parameters
Control SamplesGSM61837, GSM61838
Perturbed SamplesGSM61839, GSM61840
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE2826
Gene Expression Omnibus
Bruton's tyrosine kinase mutant models of X-linked agammaglobulinemia
14
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