Enrichment analysis of genes dysregulated in LMNA Lmna Gly609Gly knock-in
Canned Analysis
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General Information
AccessionDCA00026005
TitleEnrichment analysis of genes dysregulated in LMNA Lmna Gly609Gly knock-in
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between LMNA Lmna Gly609Gly knock-in cells and control cells in the Liver cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3090122
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvmathur
CREEDS IDgene:642
Cell TypeLiver
Gene Symbol (human)LMNA
Gene Symbol (mouse)Lmna
Organismmouse
Perturbation TypeLmna Gly609Gly knock-in
Characteristic Direction parameters
Control SamplesGSM808406, GSM808407, GSM808408
Perturbed SamplesGSM808403, GSM808404, GSM808405
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE32609
Gene Expression Omnibus
Lmna G609G knock-in model of Hutchinson-Gilford Progeria Syndrome: liver
12
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