Enrichment analysis of genes dysregulated in NOTCH1 INHIBITION
Canned Analysis
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General Information
AccessionDCA00026131
TitleEnrichment analysis of genes dysregulated in NOTCH1 INHIBITION
DescriptionAn enrichment analysis was performed on the top most dyresgulated genes determined by applying the principal angle method to compare gene expression between NOTCH1 INHIBITION cells and control cells in the MOLT4 (T-cell acute lymphoblast leukemia) cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/PAEA?id=3093499
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:88
Cell TypeMOLT4 (T-cell acute lymphoblast leukemia) cells
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismhuman
Perturbation TypeINHIBITION
Characteristic Direction parameters
Control SamplesGSM149395, GSM149396, GSM149397
Perturbed SamplesGSM149398, GSM149399, GSM149400
Tools used in the analysis
Dataset Accession
PAEA
Published November 2015
Enrichment analysis tool implementing the principal angle method
3879
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6495
Gene Expression Omnibus
T-cell acute lymphoblastic leukemia cell line response to Notch receptor inhibition
7
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