Enrichment analysis of genes upregulated following Dexamethasone treatment
Canned Analysis
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General Information
AccessionDCA00055115
TitleEnrichment analysis of genes upregulated following Dexamethasone treatment
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Dexamethasone treated cells and untreated control cells in the glucocorticoid (GC)-resistant lymphoblastic leukemia CEM-C7H2 T-ALL cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bw1j
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdrug:2488
Cell Typeglucocorticoid (GC)-resistant lymphoblastic leukemia CEM-C7H2 T-ALL cell line
Drug NameDexamethasone
DrugBank IDDB01234
Organismhuman
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM550942, GSM550943, GSM550944, GSM550945, GSM550946, GSM550947
Perturbed SamplesGSM550954, GSM550955, GSM550956, GSM550957, GSM550958, GSM550959
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE22152
Gene Expression Omnibus
Dexamethasone effect on glucocorticoid-resistant and -sensitive lymphoblastic leukemia cell lines
7
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