Enrichment analysis of genes upregulated following Chromium(iii) nicotinate treatment
Canned Analysis
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General Information
AccessionDCA00055311
TitleEnrichment analysis of genes upregulated following Chromium(iii) nicotinate treatment
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Chromium(iii) nicotinate treated cells and untreated control cells in the subcutaneous fat tissues of type 2 Lepr(db/db) mice cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1buhr
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDdrug:2590
Cell Typesubcutaneous fat tissues of type 2 Lepr(db/db) mice
Drug NameChromium(iii) nicotinate
Organismmouse
PubChem CID56843898
SMILES IDC1=CC(=CN=C1)C(=O)[O-].C1=CC(=CN=C1)C(=O)[O-].C1=CC(=CN=C1)C(=O)[O-].[Cr+3]
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM99687, GSM99688, GSM99689, GSM99690
Perturbed SamplesGSM99691, GSM99692, GSM99693, GSM99694
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4420
Gene Expression Omnibus
Niacin-bound chromium effect on the subcutaneous fat tissue of a model for type 2 diabetes with obesity
7
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