Enrichment analysis of genes downregulated following Bexarotene treatment
Canned Analysis
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General Information
AccessionDCA00055492
TitleEnrichment analysis of genes downregulated following Bexarotene treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Bexarotene treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvyf
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2680
Drug NameBexarotene
DrugBank IDDB00307
Organismhuman
PubChem CID82146
SMILES IDCC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM159355, GSM159356, GSM159357, GSM159358
Perturbed SamplesGSM159359, GSM159360, GSM159361, GSM159362
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6914
Gene Expression Omnibus
Bexarotene effect on gemcitabine resistant non-small lung cancer cell line
7
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