Enrichment analysis of genes downregulated following Bleomycin treatment
Canned Analysis
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General Information
AccessionDCA00055498
TitleEnrichment analysis of genes downregulated following Bleomycin treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Bleomycin treated cells and untreated control cells in the c57bl6j cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvry
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2685
Cell Typec57bl6j
Drug NameBleomycin
DrugBank IDDB00290
Organismmouse
PubChem CID5360373
SMILES IDCC1=C(N=C(N=C1N)C(CC(=O)N)NCC(C(=O)N)N)C(=O)NC(C(C2=CN=CN2)OC3C(C(C(C(O3)CO)O)O)OC4C(C(C(C(O4)CO)O)OC(=O)N)O)C(=O)NC(C)C(C(C)C(=O)NC(C(C)O)C(=O)NCCC5=NC(=CS5)C6=NC(=CS6)C(=O)NCCC[S+](C)C)O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM4167, GSM4168
Perturbed SamplesGSM4161, GSM4162
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE485
Gene Expression Omnibus
Pulmonary fibrosis
7
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