Enrichment analysis of genes upregulated following Decitabine treatment
Canned Analysis
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General Information
AccessionDCA00055523
TitleEnrichment analysis of genes upregulated following Decitabine treatment
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Decitabine treated cells and untreated control cells in the melanoma cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bwdn
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2703
Cell Typemelanoma
Drug NameDecitabine
DrugBank IDDB01262
Organismhuman
PubChem CID451668
SMILES IDC1C(C(OC1N2C=NC(=NC2=O)N)CO)O
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM230901, GSM230903, GSM230905, GSM230907, GSM230909, GSM230911
Perturbed SamplesGSM230902, GSM230904, GSM230906, GSM230908, GSM230910, GSM230912
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9118
Gene Expression Omnibus
DNA methylation inhibitor effect on melanoma cell lines
7
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