Enrichment analysis of genes downregulated following Dexamethasone treatment
Canned Analysis
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General Information
AccessionDCA00055524
TitleEnrichment analysis of genes downregulated following Dexamethasone treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Dexamethasone treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bv93
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2709
Drug NameDexamethasone
DrugBank IDDB01234
Organismmouse
PubChem CID5743
SMILES IDCC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM124988, GSM124989
Perturbed SamplesGSM124990, GSM124991
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5463
Gene Expression Omnibus
CD4/CD8 double positive thymocyte response to glucocorticoid
7
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