Enrichment analysis of genes downregulated following Diethylstilbestrol treatment
Canned Analysis
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General Information
AccessionDCA00055548
TitleEnrichment analysis of genes downregulated following Diethylstilbestrol treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Diethylstilbestrol treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvnt
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2718
Drug NameDiethylstilbestrol
DrugBank IDDB00255
Organismmouse
PubChem CID448537
SMILES IDCCC(=C(CC)C1=CC=C(C=C1)O)C2=CC=C(C=C2)O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM32181, GSM32182, GSM32183
Perturbed SamplesGSM32190, GSM32191, GSM32192
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1839
Gene Expression Omnibus
Uterine response to physiologic, plant-derived, and synthetic estrogen
7
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