Enrichment analysis of genes downregulated following Estradiol treatment
Canned Analysis
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General Information
AccessionDCA00055568
TitleEnrichment analysis of genes downregulated following Estradiol treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Estradiol treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvdo
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2730
Drug NameEstradiol
DrugBank IDDB00783
Organismhuman
PubChem CID5757
SMILES IDCC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM289651, GSM289652, GSM289653
Perturbed SamplesGSM289654, GSM289655, GSM289656
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11506
Gene Expression Omnibus
Estradiol effect on breast cancer cell line: time course
7
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