Enrichment analysis of genes upregulated following Imatinib treatment
Canned Analysis
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General Information
AccessionDCA00055613
TitleEnrichment analysis of genes upregulated following Imatinib treatment
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Imatinib treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bugq
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2763
Drug NameImatinib
DrugBank IDDB00619
Organismhuman
PubChem CID5291
SMILES IDCC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM577857, GSM577859, GSM577861, GSM577863
Perturbed SamplesGSM577858, GSM577860, GSM577862, GSM577913
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23743
Gene Expression Omnibus
Imatinib effect on Philadelphia chromosome positive acute lymphoblastic leukemia cells
7
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