Enrichment analysis of genes downregulated following Morphine treatment
Canned Analysis
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General Information
AccessionDCA00055640
TitleEnrichment analysis of genes downregulated following Morphine treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Morphine treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bufb
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2787
Drug NameMorphine
DrugBank IDDB00295
Organismmouse
PubChem CID5288826
SMILES IDCN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM396141, GSM396145, GSM396161, GSM396197, GSM396205, GSM396225
Perturbed SamplesGSM396131, GSM396157, GSM396173
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15774
Gene Expression Omnibus
Addictive drugs effect on brain striatum: time course
7
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