Enrichment analysis of genes downregulated following Tamoxifen treatment
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00055684
TitleEnrichment analysis of genes downregulated following Tamoxifen treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Tamoxifen treated cells and untreated control cells.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvrj
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAxel
CREEDS IDdrug:2820
Drug NameTamoxifen
DrugBank IDDB00675
Organismhuman
PubChem CID2733526
SMILES IDCCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM92147, GSM92148
Perturbed SamplesGSM92152, GSM92153, GSM92154
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE4025
Gene Expression Omnibus
Tamoxifen effect on breast cancer cell line expressing estrogen receptor alpha and beta
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.