Enrichment analysis of genes downregulated following Pbde 85 treatment
Canned Analysis
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General Information
AccessionDCA00055750
TitleEnrichment analysis of genes downregulated following Pbde 85 treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Pbde 85 treated cells and untreated control cells in the Adrenocortical carcinoma cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bw3x
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3051
Cell TypeAdrenocortical carcinoma cell line
Drug NamePbde 85
Organismhuman
PubChem CID177368
SMILES IDC1=CC(=C(C=C1Br)Br)OC2=C(C(=C(C=C2)Br)Br)Br
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM213193, GSM213194, GSM213197
Perturbed SamplesGSM213204, GSM213205, GSM213210
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8588
Gene Expression Omnibus
Polybrominated diphenyl ethers effect on adrenocortical carcinoma cell line
7
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