Enrichment analysis of genes downregulated following Fluticasone treatment
Canned Analysis
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General Information
AccessionDCA00055812
TitleEnrichment analysis of genes downregulated following Fluticasone treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Fluticasone treated cells and untreated control cells in the bronchial biopsies cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvk3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorjustinenoel
CREEDS IDdrug:3090
Cell Typebronchial biopsies
Drug NameFluticasone
Organismhuman
PubChem CID5311101
SMILES IDCC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)SCF)O)C)O)F)C)F
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM397588, GSM397589, GSM397590, GSM397591
Perturbed SamplesGSM397596, GSM397597, GSM397598, GSM397599
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15823
Gene Expression Omnibus
Inhaled corticotherapy effect on allergic asthma: bronchial biopsies
7
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