Enrichment analysis of genes downregulated following Casiigly treatment
Canned Analysis
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General Information
AccessionDCA00055884
TitleEnrichment analysis of genes downregulated following Casiigly treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Casiigly treated cells and untreated control cells in the HeLa cell line (treated with casiopeinas II-gly 40µM for 6 hours) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bv70
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3130
Cell TypeHeLa cell line (treated with casiopeinas II-gly 40µM for 6 hours)
Drug NameCasiigly
Organismhuman
PubChem CID144221079
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1025049, GSM1025050, GSM1025051
Perturbed SamplesGSM1025052, GSM1025053, GSM1025054
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE41827
Gene Expression Omnibus
HeLa cell line response to chemotherapeutic Casiopeinas
7
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