Enrichment analysis of genes upregulated following Thapsigargin treatment
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General Information
| Accession | DCA00056041 |
| Title | Enrichment analysis of genes upregulated following Thapsigargin treatment |
| Description | An enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Thapsigargin treated cells and untreated control cells in the Immortalized B cells (from MZ twin pairs - African American ancestry) cell type. |
| Analysis URL | http://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1buuu |
| Upload Date | September 20, 2017 |
| Uploader | maayanlab |
Metadata
| Analysis Curator | cadimo |
| CREEDS ID | drug:3236 |
| Cell Type | Immortalized B cells (from MZ twin pairs - African American ancestry) |
| Drug Name | Thapsigargin |
| Organism | human |
| PubChem CID | 446378 |
| SMILES ID | CCCCCCCC(=O)OC1C2C(=C(C1OC(=O)C(=CC)C)C)C3C(C(CC2(C)OC(=O)C)OC(=O)CCC)(C(C(=O)O3)(C)O)O |
Characteristic Direction parameters
| Gene Set | upregulated |
| Gene Set Size | 500 |
| Control Samples | GSM494452, GSM494454, GSM494456, GSM494458, GSM494460, GSM494462, GSM494464, GSM494466, GSM494468, GSM494470, GSM494472, GSM494474, GSM494476, GSM494478, GSM494480, GSM494482, GSM494484, GSM494486, GSM494488, GSM494490, GSM494492, GSM494494, GSM494496, GS |
| Perturbed Samples | GSM494453, GSM494455, GSM494457, GSM494459, GSM494461, GSM494463, GSM494465, GSM494467, GSM494469, GSM494471, GSM494473, GSM494475, GSM494477, GSM494479, GSM494481, GSM494483, GSM494485, GSM494487, GSM494489, GSM494491, GSM494493, GSM494495, GSM494497, GS |
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