Enrichment analysis of genes upregulated following Phorbol ester 12-o-tetradecanoylphorbol-13-acetate (tpa) treatment
Canned Analysis
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General Information
AccessionDCA00056065
TitleEnrichment analysis of genes upregulated following Phorbol ester 12-o-tetradecanoylphorbol-13-acetate (tpa) treatment
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between Phorbol ester 12-o-tetradecanoylphorbol-13-acetate (tpa) treated cells and untreated control cells in the dorsal skin cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvsn
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorPascal
CREEDS IDdrug:3256
Cell Typedorsal skin
Drug NamePhorbol ester 12-o-tetradecanoylphorbol-13-acetate (tpa)
Organismmouse
PubChem CID27924
SMILES IDCCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1003251, GSM1003252, GSM1003253
Perturbed SamplesGSM1003248, GSM1003249, GSM1003250
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40849
Gene Expression Omnibus
Phorbol ester effect on skin of Rho exchange factor Vav2/Vav3 double knockout mutants: time course
7
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