Enrichment analysis of genes downregulated following Carbidopa treatment
Canned Analysis
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General Information
AccessionDCA00056168
TitleEnrichment analysis of genes downregulated following Carbidopa treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Carbidopa treated cells and untreated control cells in the jeujunum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bv0p
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgaribr01
CREEDS IDdrug:3293
Cell Typejeujunum
Drug NameCarbidopa
DrugBank IDDB00190
Organismmouse
SMILES IDNN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C.O
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1144771, GSM1144772, GSM1144773, GSM1144777, GSM1144778, GSM1144779
Perturbed SamplesGSM1144768, GSM1144769, GSM1144770, GSM1144774, GSM1144775, GSM1144776
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47099
Gene Expression Omnibus
Cholestatic intestinal injury model: jejunum
7
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