Enrichment analysis of genes downregulated following Progesterone treatment
Canned Analysis
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General Information
AccessionDCA00056490
TitleEnrichment analysis of genes downregulated following Progesterone treatment
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between Progesterone treated cells and untreated control cells in the Ovaries - cultured neonatal ovaries treated with progesterone for 2 days cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bvdi
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdrug:3526
Cell TypeOvaries - cultured neonatal ovaries treated with progesterone for 2 days
Drug NameProgesterone
DrugBank IDDB00396
Organismrat
PubChem CID5994
SMILES IDCC(=O)C1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM203966, GSM203967
Perturbed SamplesGSM203968, GSM203969
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8238
Gene Expression Omnibus
Progesterone effect on cultured neonatal ovaries
7
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