Enrichment analysis of genes downregulated in sickle cell anemia
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00059545
TitleEnrichment analysis of genes downregulated in sickle cell anemia
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by sickle cell anemia and healthy control cells in the Endothelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsvd
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:109
Cell TypeEndothelial cell
DO IDDOID:10923
Disease Namesickle cell anemia
Organismhuman
UMLS CUIC0002895
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM249425, GSM249426, GSM249427, GSM249428, GSM249429, GSM249430, GSM249431, GSM249432, GSM249433, GSM249434, GSM249435, GSM249436, GSM249437, GSM249438, GSM249439, GSM249440, GSM249441, GSM249442, GSM249443, GSM249444, GSM249445, GSM249446, GSM249447, GS
Perturbed SamplesGSM249452, GSM249453, GSM249454, GSM249455, GSM249456, GSM249457, GSM249458, GSM249459, GSM249460, GSM249461, GSM249462, GSM249463, GSM249464, GSM249465, GSM249466, GSM249467, GSM249468, GSM249469, GSM249470, GSM249471
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9877
Gene Expression Omnibus
Genetic Endothelial Systems Biology of Sickle Stroke Risk
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.