Enrichment analysis of genes downregulated in familial combined hyperlipidemia
Canned Analysis
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General Information
AccessionDCA00059597
TitleEnrichment analysis of genes downregulated in familial combined hyperlipidemia
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by familial combined hyperlipidemia and healthy control cells in the lymphoblast cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsh1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:137
Cell Typelymphoblast
DO IDDOID:13809
Disease Namefamilial combined hyperlipidemia
Organismhuman
UMLS CUIC0020474
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM15814, GSM15815, GSM15816, GSM15817, GSM15820, GSM15867, GSM15868, GSM15869, GSM15871, GSM15873, GSM15874, GSM15876
Perturbed SamplesGSM15808, GSM15809, GSM15810, GSM15811, GSM15812, GSM15813, GSM15818, GSM15819, GSM15866, GSM15870, GSM15872, GSM15875
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1010
Gene Expression Omnibus
Familial combined hyperlipidemia
7
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