Enrichment analysis of genes downregulated in chronic lymphocytic leukemia
Canned Analysis
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General Information
AccessionDCA00059717
TitleEnrichment analysis of genes downregulated in chronic lymphocytic leukemia
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by chronic lymphocytic leukemia and healthy control cells in the Peripheral blood mononuclear cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1btm9
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:194
Cell TypePeripheral blood mononuclear cell
DO IDDOID:1040
Disease Namechronic lymphocytic leukemia
Organismhuman
UMLS CUIC0023458
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM219478, GSM219479, GSM219480, GSM219481, GSM219482, GSM219483, GSM219484, GSM219485, GSM219486, GSM219487, GSM219488, GSM219489, GSM219510, GSM219511, GSM219512, GSM219513, GSM219514, GSM219515, GSM219516, GSM219517, GSM219518, GSM219519, GSM219520, GS
Perturbed SamplesGSM219456, GSM219457, GSM219458, GSM219459, GSM219460, GSM219461, GSM219462, GSM219463, GSM219464, GSM219465, GSM219466, GSM219467, GSM219468, GSM219469, GSM219470, GSM219471, GSM219472, GSM219473, GSM219474, GSM219475, GSM219476, GSM219477, GSM219490, GS
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8835
Gene Expression Omnibus
Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells.
7
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