Enrichment analysis of genes upregulated in ankylosing spondylitis
Canned Analysis
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General Information
AccessionDCA00059742
TitleEnrichment analysis of genes upregulated in ankylosing spondylitis
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by ankylosing spondylitis and healthy control cells in the macrophage cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bso3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:202
Cell Typemacrophage
DO IDDOID:7147
Disease Nameankylosing spondylitis
Organismhuman
UMLS CUIC0038013
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM300398, GSM300399, GSM300400, GSM300401, GSM300402, GSM300403, GSM300404, GSM300405, GSM300406
Perturbed SamplesGSM300414, GSM300415, GSM300416, GSM300417, GSM300418, GSM300419, GSM300420, GSM300421
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11886
Gene Expression Omnibus
Gene expression analysis of macrophages from ankylosing spondylitis patients reveals interferon-gamma dysregulation
7
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