Enrichment analysis of genes downregulated in type 2 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00059853
TitleEnrichment analysis of genes downregulated in type 2 diabetes mellitus
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by type 2 diabetes mellitus and healthy control cells in the Renal Tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1btyo
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:25
Cell TypeRenal Tissue
DO IDDOID:9352
Disease Nametype 2 diabetes mellitus
Organismmouse
UMLS CUIC0011860
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM10401, GSM9059, GSM9069, GSM9070, GSM9071, GSM9072, GSM9073, GSM9074, GSM9075, GSM9076, GSM9169, GSM9170, GSM9171, GSM9172, GSM9173
Perturbed SamplesGSM9077, GSM9078, GSM9079, GSM9080, GSM9081, GSM9082, GSM9083, GSM9084, GSM9085, GSM9086, GSM9087, GSM9088, GSM9089, GSM9090, GSM9091, GSM9092, GSM9143, GSM9144, GSM9145, GSM9146, GSM9147, GSM9148, GSM9149, GSM9150, GSM9151, GSM9152, GSM9153, GSM9154, GSM
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE710
Gene Expression Omnibus
Diabetic nephropathy: models of type 1 and type 2 diabetes
7
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